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Warning signs predict kidney injury after surgery

Acute kidney injury (AKI) is a common – but preventable -- complication after surgery that can lead to other complications or even death. The use and development of biomarkers will help physicians diagnose and treat ...

Diseases, Conditions, Syndromes

Tyrosine kinase inhibitors seem safe in CML with CKD

(HealthDay)—Tyrosine kinase inhibitors (TKIs) appear to be safe in patients with chronic-phase (CP) chronic myeloid leukemia (CML) and chronic kidney disease (CKD), according to a study published online July 28 in Cancer.

Diseases, Conditions, Syndromes

New therapeutic targets for kidney fibrosis emerge

Chronic kidney disease is a global health concern, affecting about 10 percent of the world's population—and increasing in prevalence. A final, common pathway in chronic kidney disease is fibrosis. Just as fibrosis—or ...

Medical research

'Goldilocks' drug prevents chronic kidney disease in primates

Cells in any organ will die if their blood supply is cut off - such as during a heart attack, stroke, or organ transplant - but restoring circulation can also cause damage. Now a Massachusetts General Hospital (MGH) research ...

Medical research

COVID-19 can directly infect and damage human kidney cells

The virus that causes COVID-19, SARS-CoV-2, can directly infect a specialized type of kidney cell. The discovery helps explain why acute kidney injury is one of the main complications observed in patients with severe COVID-19, ...

Immunology

Malnutrition-linked inflammation of the gut

More than one billion people in poor countries are starving, and malnutrition remains a major problem even in rich countries, making it a leading cause of death in the world. For over a hundred years, doctors have known that ...

Diseases, Conditions, Syndromes

Mitochondrial metabolism linked to acute kidney injury

Approximately one out of five hospitalized adults and one out of three hospitalized children worldwide experience acute kidney injury, the sudden loss of kidney function. Many different factors, including surgery, chemotherapy ...

Diseases, Conditions, Syndromes

COVID-19: Long-term consequences for the kidneys can be expected

The kidneys are a target organ of COVID-19 and are affected very early in the course. However, this is precisely where there is strong prognostic potential: As early as last spring, COVID-19-associated nephritis was identified ...

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