Health

Patient CKD app ratings do correlate with those of nephrologists

(HealthDay)—Patient ratings of chronic kidney disease (CKD) apps are not directly linked with nephrologist ratings or consumer ratings, according to a study published online March 21 in the Clinical Journal of the American ...

Diseases, Conditions, Syndromes

NUP160 genetic mutation linked to steroid-resistant nephrotic syndrome

Mutations in the NUP160 gene, which encodes one protein component of the nuclear pore complex nucleoporin 160 kD, are implicated in steroid-resistant nephrotic syndrome, an international team reports March 25, 2019, in JASN. ...

Diseases, Conditions, Syndromes

Peptide shows promise for protecting kidneys from nephritis

A synthetic peptide appears to directly disrupt the destructive inflammation that occurs in nephritis, enabling the kidneys to better recover and maintain their important functions, investigators report.

Diseases, Conditions, Syndromes

Poor kidney function linked to higher cancer risk

A new study has uncovered a modestly higher cancer risk in individuals with mild to severe chronic kidney disease, driven primarily by skin (non-melanoma) and urogenital cancers. The findings, which appear in an upcoming ...

Diseases, Conditions, Syndromes

Study provides new insights on common post-transplant condition

New research may help clinicians determine which patients with a condition that commonly arises after kidney transplantation are at high risk of transplant failure. The findings appear in an upcoming issue of the Journal ...

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Kidney

The kidneys are paired organs, which have the production of urine as their primary function. Kidneys are seen in many types of animals, including vertebrates and some invertebrates. They are part of the urinary system, but have several secondary functions concerned with homeostatic functions. These include the regulation of electrolytes, acid-base balance, and blood pressure. In producing urine, the kidneys excrete wastes such as urea and ammonium; the kidneys also are responsible for the reabsorption of glucose and amino acids. Finally, the kidneys are important in the production of hormones including vitamin D, renin and erythropoietin.

Located behind the abdominal cavity in the retroperitoneum, the kidneys receive blood from the paired renal arteries, and drain into the paired renal veins. Each kidney excretes urine into a ureter, itself a paired structure that empties into the urinary bladder.

Renal physiology is the study of kidney function, while nephrology is the medical specialty concerned with diseases of the kidney. Diseases of the kidney are diverse, but individuals with kidney disease frequently display characteristic clinical features. Common clinical presentations include the nephritic and nephrotic syndromes, acute kidney failure, chronic kidney disease, urinary tract infection, nephrolithiasis, and urinary tract obstruction.

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