Medical research

Brief dialysis may be best for some kidney patients

Patients with acute kidney injury requiring outpatient dialysis after hospital discharge receive the same care as those with the more common end-stage kidney disease, according to a study led by UC San Francisco.

Diseases, Conditions, Syndromes

New research: Acute kidney damage spreads over time

When our kidneys are acutely damaged, it can cause necrotic injury, which is the death of cells in the kidney. A new study from Aarhus University has now found that the cell damage spreads over several days after the immediate ...

Medications

Uromodulin levels may indicate risk for kidney failure

Prior studies of uromodulin, the most abundant protein in urine, and kidney disease have focused primarily on urinary uromodulin levels. A study, published in the American Journal of Kidney Diseases (AJKD), evaluated associations ...

Genetics

Women with gene mutation give new insight into blood clot risk

New research from Queen Mary University of London, published in iScience, shows an increased risk of blood clots in women who have any combination of a particular gene mutation, estrogen use, or common medical conditions—specifically: ...

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Kidney

The kidneys are paired organs, which have the production of urine as their primary function. Kidneys are seen in many types of animals, including vertebrates and some invertebrates. They are part of the urinary system, but have several secondary functions concerned with homeostatic functions. These include the regulation of electrolytes, acid-base balance, and blood pressure. In producing urine, the kidneys excrete wastes such as urea and ammonium; the kidneys also are responsible for the reabsorption of glucose and amino acids. Finally, the kidneys are important in the production of hormones including vitamin D, renin and erythropoietin.

Located behind the abdominal cavity in the retroperitoneum, the kidneys receive blood from the paired renal arteries, and drain into the paired renal veins. Each kidney excretes urine into a ureter, itself a paired structure that empties into the urinary bladder.

Renal physiology is the study of kidney function, while nephrology is the medical specialty concerned with diseases of the kidney. Diseases of the kidney are diverse, but individuals with kidney disease frequently display characteristic clinical features. Common clinical presentations include the nephritic and nephrotic syndromes, acute kidney failure, chronic kidney disease, urinary tract infection, nephrolithiasis, and urinary tract obstruction.

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