Medical research
New gears in your sleep clock
The circadian cycle, a long-studied factor controlling human sleep cycles, actually has two forms, one that keeps a key protein stable, and another that promotes its degradation.
Jul 12, 2018
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Page 23 - News tagged with kinases
Medical research
New model for predicting neuroblastoma outcomes incorporates early developmental signals
Neuroblastoma, a rare childhood cancer of the sympathetic nervous system, is particularly deadly because it is difficult to detect and thus generally advanced before treatment begins. Scientists know that neuroblastoma develops ...
Jul 6, 2018
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Neuroscience
New nuclear medicine technique could help tackle brain disease
A new molecular imaging method can monitor the success of gene therapy in all areas of the brain, potentially allowing physicians to more effectively tackle brain conditions such as Parkinson's disease, Alzheimer's disease ...
Jun 25, 2018
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Oncology & Cancer
'Embattled' breast cancer drugs could be revived by new discovery
More than 60 percent of breast cancer cases involve defects in the same biochemical chain of events within cancer cells—known as the PI3 kinase (PI3K) pathway—but efforts to develop therapies targeting this pathway have ...
Jun 25, 2018
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Oncology & Cancer
PIM-2 protein kinase regulates T-cell activity differently than PIM-1 or PIM-3 isoform
The PIM-2 protein kinase negatively regulates T cell responses in transplantation and tumor immunity, while PIM-1 and PIM-3 are positive regulators, report Medical University of South Carolina (MUSC) investigators in an article ...
Jun 15, 2018
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Oncology & Cancer
Genes of different importance for brain cancer
Two genes play important roles for the formation of malignant cancer in the brain. One gene prevents the formation of the tumour, while another gene promotes the tumour. This is shown in a new dissertation at Umeå University, ...
May 24, 2018
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Diabetes
Diabetes researchers find switch for fatty liver disease
Duke researchers have identified a key fork in the road for the way the liver deals with carbohydrates, fats and protein. They say it could be a promising new target for combating the pandemics of fatty liver disease and ...
May 17, 2018
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Oncology & Cancer
Researchers uncover up to 100 potential drug targets for cancer
Protein researchers from the Novo Nordisk Foundation Center for Protein Research at the University of Copenhagen have used mass spectrometry-based proteomics to uncover a number of proteins that could play a critical role ...
May 15, 2018
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Oncology & Cancer
Largest-ever study of thyroid cancer genetics finds new mutations, suggests immunotherapy
University of Colorado Cancer Center researchers recently completed the largest-ever study of thyroid cancer genetics, mining the data of 583 patient samples of advanced differentiated thyroid cancer and 196 anaplastic thyroid ...
Apr 26, 2018
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Oncology & Cancer
Three solutions to maximize the clinical benefit and affordability of targeted cancer drugs
Spending on cancer drugs in the United States has nearly doubled in the past five years and continues to grow, imposing substantial financial burden on patients with cancer. One of the biggest drivers of this growth is targeted ...
Apr 18, 2018
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