Oncology & Cancer

Unraveling the genetic causes of skin cancer

Skin cancer is on the rise in the United States. Squamous cell carcinoma, the second most common form of cancer in the U.S., has the highest mortality rate of all non-melanoma skin cancers. In roughly two to five percent ...

Cardiology

Enzyme protects against obesity-related heart disease

Saturated fats found in high-fat diets increase the risk of heart failure. Now Manisha Gupte, PhD, Hind Lal, PhD, and colleagues show that the presence of an enzyme called GSK-3beta in the heart is crucial to protect against ...

Diabetes

Discovery may be key to obesity, diabetes Rx

Research led by Suresh Alahari, PhD, Fred Brazda Professor of Biochemistry and Molecular Biology at LSU Health New Orleans School of Medicine, has demonstrated the potential of a protein to treat or prevent metabolic diseases ...

Neuroscience

An immune regulator of addiction

Drug addiction is often thought of as neuron-centric, but in a study published in the Proceedings of the National Academy of Sciences, M.D./Ph.D. student Daniel Kashima and his mentor, Brad Grueter, Ph.D., show that the immune ...

Genetics

Promising mouse model for a devastating genetic deficiency

Researchers from the RIKEN Global Research Cluster in Japan have developed a potential mouse model for the genetic disorder known as an NGLY1 deficiency. Published in the journal PLOS Genetics, the study describes how a complete ...

Ophthalmology

GARP2 accelerates retinal degeneration in a mouse model

In the retina of the eye, rod and cone cells turn light into electrical signals, the first step toward human vision. University of Alabama at Birmingham researchers are studying rod cell proteins GARP1 and GARP2 to learn ...

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