A new study by researchers at University of Illinois Chicago suggests that when the protein optineurin, or OPTN, is present in cells it restricts the spread of HSV-1, the herpes simplex virus type 1.
Sep 13, 2021
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223
Growing evidence indicates that gut microbiota plays a critical role in regulating the progression of neurodegenerative diseases such as Parkinson's disease (PD) and Alzheimer's disease (AD), but the molecular mechanism underlying ...
Sep 7, 2021
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539
Understanding the role of tau protein in Alzheimer's disease (AD) has led to new ways to diagnose it as well as the creation of medicines now in clinical trials to treat it.
Aug 27, 2021
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430
Scientists at the Francis Crick Institute and UCL have studied how proteins accumulate in the wrong parts of brain cells in motor neuron disease, and have demonstrated how it might be possible, in some cases, to reverse this.
Aug 6, 2021
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848
Researchers in Singapore have discovered that brain cells cannot maintain the cholesterol-rich myelin sheath that protects and insulates neurons in the absence of a protein called TDP-43. The study, which will be published ...
Aug 4, 2021
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82
Researchers at the UAB describe the mechanism through which a non-toxic derivative of the tetanus neurotoxin (Hc-TeTx) may serve to treat depression and neurodegenerative diseases, as has already been demonstrated in animal ...
Jul 9, 2021
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7
Amyotrophic lateral sclerosis, or ALS, attacks nerve cells known as motor neurons in the brain and spinal cord, gradually leading to paralysis. The loss of function of an important gene, C9orf72, may affect communication ...
Jun 30, 2021
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6
A UCLA-led study comparing brain cells known as astrocytes in humans and mice found that mouse astrocytes are more resilient to oxidative stress, a damaging imbalance that is a mechanism behind many neurological disorders. ...
Jun 25, 2021
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2
A new University of California, Irvine-led study finds that the persistence of a marker of chronic cellular stress, previously associated with neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal ...
Jun 23, 2021
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21
Researchers rescued mice from early death caused by a muscle-weakening disease, not by correcting the flawed gene that causes it, but instead by targeting another protein in the same signaling pathway.
Jun 23, 2021
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10
