Targeting apolipoprotein B (APOB) gene has not been tested in clinical trials for cardiovascular outcomes because of risk of fatty liver disease, but naturally-occurring mutation suggests it may be effective.
May 13, 2019
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Lowering low-density lipoprotein (LDL) cholesterol reduces the risk of heart attacks and stroke, with an ideal value below 100 milligrams per deciliter (mg/dL). But can it be too low? A new study finds that women who have ...
Apr 10, 2019
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Patients at high risk for a heart attack or stroke who took an investigational drug in addition to a statin had significantly lower LDL, or "bad" cholesterol, after 12 weeks compared to similar patients who took a placebo ...
Mar 18, 2019
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People whose high cholesterol is resistant to treatment with statin drugs may soon have a new treatment option.
Mar 14, 2019
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Atherosclerosis is a tough problem—arteries get thicker and stiffer, which can lead to heart disease and stroke, but it is not known precisely how cholesterol causes this thickening. Cholesterol is a tiny fat molecule that ...
Mar 1, 2019
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A major Cardiovascular (CV) risk factor is low-density Lipoprotein Cholesterol (LDL-C). A lot of evidence that was accumulated supports a linear association between LDL-C levels and CV risk. However, whether the lower limit ...
Jan 2, 2019
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(HealthDay)—High cholesterol, a serious risk factor for heart disease, can affect both men and women, and it's common for cholesterol levels to rise with age. But it's often a problem for men earlier in life than for women.
Dec 17, 2018
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Thousands of heart attacks and deaths from cardiovascular disease could be prevented by patients taking higher doses of statins and taking the drugs as advised by doctors.
Dec 7, 2018
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In a clinical trial involving 18,924 patients from 57 countries who had suffered a recent heart attack or threatened heart attack, researchers at the University of Colorado Anschutz Medical Campus and fellow scientists around ...
Nov 7, 2018
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A new review of published research from an international group of physicians and researchers is challenging the half-century long belief that LDL, the so-called 'bad kind' of cholesterol, causes heart disease.
Oct 1, 2018
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