Obstetrics & gynaecology

Mouse study hints at specific brain receptor behind PCOS symptoms

Polycystic ovarian syndrome, or PCOS, can cause a range of symptoms, including disrupted menstrual cycles, abdominal obesity, cardiovascular disease, and type 2 diabetes. It's also one of the biggest causes of infertility—in ...

Medical research

Obese inducing brain mechanism

Leptin is an adipocyte-derived hormone that stimulates hypothalamic neurons to strongly inhibit food intake. Leptin signaling in the hypothalamus, a part of the mid-brain, thus plays a crucial role in the regulation of body ...

Overweight & Obesity

Gut-brain connection helps explain how overeating leads to obesity

Eating extra servings typically shows up on the scale later, but how this happens has not been clear. A new study published today in the Journal of Clinical Investigation by a multi-institutional team led by researchers at ...

Medical research

Target for obesity drugs comes into focus

(Medical Xpress)—Researchers at the University of Michigan have determined how the hormone leptin, an important regulator of metabolism and body weight, interacts with a key receptor in the brain.

Medical research

A new drug to help young patients with genetic obesity

In a new study, researchers from the Institute for Experimental Pediatric Endocrinology of the Charité - Universitätsmedizin Berlin have successfully treated patients whose obesity is caused by a genetic defect. Aside from ...

Medical research

Leptin suppresses the rewarding effects of running

(HealthDay)—Leptin appears to inhibit running reward via signal transducer and activator of transcription-3 (STAT3), according to an experimental study published online Sept. 1 in Cell Metabolism.

Medical research

Researchers develop cell line to study obesity, other diseases

A Kansas State University research team has created a cell line that can be used in studies aimed at understanding obesity and other disease in humans, a discovery that has caught the attention of a Canadian company that ...

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