Researchers led by a UCLA bioengineer have developed a therapy—based on two types of cells joined into a single unit—that could help strengthen existing treatments for acute myeloid leukemia. One of the cells is a blood ...
Oct 30, 2018
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New research describes how highly proliferative leukemia cells end up becoming normal cells that no longer multiply, by changing the chemical modifications—the so-called epigenetics—of a type of its genetic material: ...
Jun 9, 2022
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Survival has improved greatly in children with acute lymphocytic leukemia (ALL). But a certain form of ALL that occurs mostly in babies is still very lethal, with a survival rate below 50 percent: B-cell acute lymphoblastic ...
Jun 1, 2022
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Leukemia starts in cells that would normally develop into different types of blood cells. About 61,000 people in the U.S. are diagnosed each year, and depending on the type of leukemia and the age of the patient, five-year ...
Jun 8, 2022
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By studying rare cases of identical twins with leukemia, scientists have shed new light on the origins of the most common type of childhood cancer—confirming it originates in the womb but that events after birth determine ...
Dec 20, 2022
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Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS), and increasingly in other diseases, but their mechanism of action is not clear. HMAs may affect many ...
May 26, 2022
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All human tumors originating from various tissues share a series of properties that define them, including the ability to prevent cell death. Instead, healthy organs induce programmed cell death or apoptosis to balance their ...
Aug 1, 2022
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Despite tremendous advances in medicine, tumors are challenging to cure because they are made up of heterogeneous cells. In other words, like human families, the individual cells of a tumor share some common traits and characteristics, ...
Aug 13, 2021
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Tyrosine kinases are protein enzymes that have many functions within cells, including cell signaling, growth, and division. Sometimes these enzymes can be overactive, which helps cancer cells survive and multiply. A tyrosine ...
Jul 31, 2020
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(Medical Xpress) -- Researchers in the Department of Pathology at Stony Brook University School of Medicine have discovered a laboratory method to expand adult hematopoietic stem cells (HSCs) using the SALL4 gene. Professor ...
Jun 7, 2011
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