Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant ...
Feb 16, 2023
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According to a popular saying, 'timing is everything.' For acute myeloid leukemia (AML), that adage may be true. In a paper published in the April 7 issue of Cell, an international team led by researchers from the Broad Institute ...
Apr 8, 2016
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Scientists at St. Jude Children's Research Hospital developed a strategy to improve the ability of engager (ENG) T cells to kill acute myeloid leukemia (AML). The approach showed promise in preclinical models against hard-to-treat ...
Jul 29, 2022
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An inflammatory signaling protein called interleukin-6 has been linked to the progression of acute myeloid leukemia, representing a potential target for future treatments of the disease, according to a recent Northwestern ...
Aug 16, 2022
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In a paper, "Epitope editing enables targeted immunotherapy of acute myeloid leukaemia," published in Nature, researchers at the Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, introduce a genetic ...
There could be new treatments on the horizon for diffuse intrinsic pontine glioma, or DIPG, a devastating form of brain cancer that afflicts young children and is currently incurable. Recent experiments in animal models of ...
Apr 4, 2019
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A new study led by researchers at the University of Kentucky Markey Cancer Center and UK Department of Pharmacology and Nutritional Sciences demonstrates the potential benefit of using an anti-leukemic drug nilotinib—most ...
Oct 30, 2020
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A significant number of non-Hodgkin lymphoma (NHL) patients in a Penn Medicine-initiated clinical trial continue to be in remission five years after receiving the chimeric antigen receptor (CAR) T cell therapy Kymriah, researchers ...
Feb 18, 2021
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New research has begun to unravel the mystery of why a particular form of leukemia in infants has defied efforts to improve outcomes, despite significant improvements in treating older children. Scientists from the Wellcome ...
Mar 14, 2022
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A new discovery in Ewing sarcoma, an aggressive and often fatal childhood cancer, has uncovered the potential to prevent cancer cells from spreading beyond their primary tumor site.
Jun 1, 2021
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