Cells contain diverse populations of molecules called lipids, which are organic fatty compounds. Lipid metabolism, the synthesis and breakdown of these lipids, plays a key role in regulating the composition and functions ...
Mar 30, 2023
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Leukemia, a type of blood cancer, affected around 2.3 million people around the world in 2015. Acute myeloid leukemia (AML)—a particularly aggressive disease—generally starts in the bone marrow, when stem cells cannot ...
Jan 31, 2023
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Every year, up to 1% of patients with chronic lymphocytic leukemia (CLL), a slow-growing blood cancer, have their disease transform into a far more aggressive cancer, a form of lymphoma known as Richter's syndrome. For the ...
Dec 12, 2022
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For Kristin Kleinhofer, two words—"choose hope"—have been a lifeline.
Apr 27, 2016
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(Medical Xpress)—Imagine that a police bomb squad comes upon a diabolically designed bomb controlled by a tangled mass of different wires, lights and switches, some of which have a real function while others are decoys. ...
Aug 30, 2012
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Researchers from The University of Texas MD Anderson Cancer Center showed that inhibiting menin with revumenib, previously known as SNDX-5613, yielded encouraging responses for advanced acute leukemias with KMT2A rearrangements ...
Mar 15, 2023
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Researchers in Germany have discovered that a tumor suppressor protein thought to prevent acute myeloid leukemia (AML) can actually promote a particularly deadly form of the disease. The study, "RUNX1 cooperates with FLT3-ITD ...
Feb 17, 2017
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A team of researchers at Cold Spring Harbor Laboratory (CSHL) has identified a leukemia-specific stretch of DNA called an enhancer element that enables cancerous blood cells to proliferate in Acute Myeloid Leukemia (AML), ...
Nov 26, 2013
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New research conducted at UNC Lineberger Comprehensive Cancer Center, offers hope for people with a rare disorder called Chuvash polycythemia.
Jun 22, 2011
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Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. This disease includes two subtypes, B-cell and T-cell leukemia, depending upon the type of white blood cell where the leukemia originates. For B-cell ...
May 14, 2015
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