Neuroscience
Researchers solve mystery of how ALL enters the central nervous system
A deadly feature of acute lymphoblastic leukemia (ALL) is its invasion of the central nervous system.
Jul 18, 2018
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Page 7 - News tagged with leukemia drug
Medications
Finding second hits to knock out leukemia
Many new anti-cancer drugs inhibit proteins that are essential for the proliferation of cancer cells. One example is ibrutinib, an innovative therapy for chronic lymphocytic leukemia first approved in 2014. Chronic lymphocytic ...
Jan 29, 2019
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Oncology & Cancer
Exploring novel mechanisms and therapeutic targets for acute myeloid leukemia
Patients with acute myeloid leukemia, the most common type of adult blood cancer, show large-scale genomic mutations and altered DNA folding patterns that could help identify potential therapeutic targets, according to a ...
Oct 28, 2022
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Medications
Researchers say chemo drug may prevent heart failure
A chemotherapy drug used to fight bone-marrow cancer has the potential to treat and prevent potentially deadly heart failure, a powerful new drug-screening tool developed at UVA Health suggests.
Sep 18, 2023
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Oncology & Cancer
Antibody-guided drug works against acute lymphoblastic leukemia
An antibody packaged with a potent chemotherapy drug to selectively destroy acute lymphoblastic leukemia (ALL) cells eradicated or greatly reduced the disease for 61 percent of 46 patients in a phase II study. It will be ...
May 23, 2011
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Oncology & Cancer
Evolution may hold the key to more designer cancer drugs like Gleevec
This is the story of Abl and Src—two nearly identical protein kinases whose evolution may hold the key to unlocking new, highly specific cancer drugs.
Feb 19, 2015
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Oncology & Cancer
New hope for reduced long-term side effects in children after leukemia treatment
By using drugs currently used to treat other diseases, scientists hope they will help children with leukemia suffer fewer long-term aftereffects from their treatment.
Aug 31, 2022
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Oncology & Cancer
Breakthrough drug on fast-track to help leukemia patients
Three very different people gathered recently at University of Colorado Hospital. They were linked by leukemia.
Feb 28, 2014
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Oncology & Cancer
How a leukemia hijacks the genes needed by blood stem cells
As a child, Lynn Aureli didn't know that a particular genetic change contributed to her acute myeloid leukemia (AML)—an alteration that eventually would help explain the cancer's lack of response to chemotherapy. Nor was ...
Jan 27, 2023
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Medical research
New drug combination shows promise as powerful treatment for AML
Scientists have identified two drugs that are potent against acute myeloid leukemia (AML) when combined, but only weakly effective when used alone. The researchers were able to significantly enhance cancer cell death by jointly ...
Jan 19, 2021
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