Hyperdiploidy is a genetic condition observed in cancer cells, where the cells contain more chromosomes than usual. The condition is particularly prevalent in childhood B-cell acute lymphoblastic leukemia (B-ALL), the most ...
Sep 20, 2023
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A chemotherapy drug used to fight bone-marrow cancer has the potential to treat and prevent potentially deadly heart failure, a powerful new drug-screening tool developed at UVA Health suggests.
Sep 18, 2023
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A new editorial paper titled "Decoding the mechanism behind MCL-1 inhibitors: A pathway to understanding MCL-1 protein stability" has been published in Oncotarget.
Jun 28, 2023
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Tiny packets of molecular cargo shed by cancer cells seed the foundations for metastasis at distant sites in the body.
Jun 19, 2023
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Targeted drugs have been developed to supplement chemotherapy in the treatment of cancer. These drugs only affect cancer cells, leaving healthy cells alone. Venetoclax is a new targeted therapy option for the treatment of ...
Feb 23, 2023
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The U.S. Food and Drug Administration has approved zanubrutinib (Brukinsa), a next-generation BTK inhibitor, for the treatment of patients with chronic lymphocytic leukemia or small lymphocytic lymphoma.
Jan 24, 2023
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Cambridge scientists have managed to identify and kill those breast cancer cells that evade standard treatments in a study in mice. The approach is a step towards the development of new treatments to prevent relapse in patients.
Dec 20, 2022
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Researchers at The Tisch Cancer Institute uncovered inflammatory markers that may predict which COVID-19 patients are more likely to respond to therapies like the anti-cancer drug pacritinib, according to phase 2 trial results ...
Dec 5, 2022
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For years, brand drug companies have been villainized for "evergreening" or manipulating the law to extend the period of exclusivity for drugs beyond their 20-year patent—a practice critics say unfairly prevents competition ...
Nov 3, 2022
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By using drugs currently used to treat other diseases, scientists hope they will help children with leukemia suffer fewer long-term aftereffects from their treatment.
Aug 31, 2022
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