Oncology & Cancer

Targeting "anti-tumor" genes to provide better treatment for leukemia

Chronic lymphocytic leukemia (CLL) is one of the most common blood cancers in adults. The disease originates in B cells—the part of the immune system that produces antibodies—and then evolves slowly, typically affecting ...

Medications

Rewiring the biology of leukemia cells to reverse drug resistance

Researchers from Barts Cancer Institute at Queen Mary University of London have identified a way to reverse resistance to a group of cancer drugs, known as kinase inhibitors, in leukemia cells. By rewiring the inner workings ...

Medical research

Resistance mechanisms to CAR-T cell therapy ID'd in ALL

For patients with acute lymphoblastic leukemia with resistance to C19 CAR T-cell therapy, resistance mechanisms that can be detected prior to treatment have been identified, according to a study presented at the annual meeting ...

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