MIT biological engineers have created a multitissue model that lets them study the relationships between different organs and the immune system, on a specialized microfluidic platform seeded with human cells.
Mar 18, 2020
0
104
Cancer-promoting genes MYC and TWIST1 co-opt immune system cells to enable cancer cells to spread, but blocking a key step in this process can help prevent the disease from developing.
Jan 14, 2020
0
210
Alagille syndrome is a rare pediatric genetic disorder that can affect the liver, heart, kidneys, blood vessels, skeleton and other tissues. One major characteristic of this condition is abnormalities in the ducts that carry ...
Oct 11, 2019
0
24
Having too much caffeine during pregnancy may impair baby's liver development and increase the risk of liver disease in adulthood, according to a study published in the Journal of Endocrinology. Pregnant rats given caffeine ...
Jul 24, 2019
0
0
Duke-NUS researchers have found evidence that a natural form of Docosahexaenoic Acid (DHA) made by the liver called Lyso-Phosphatidyl-Choline (LPC-DHA), is critical for normal foetal and infant brain development, and that ...
Aug 17, 2018
0
425
The real danger of separating children from parents is not the psychological stress – it's the biological time bomb. The screaming and crying, the anguish and desolation is gut-wrenching. But the fallout pales in comparison ...
Jun 28, 2018
0
142
Lipids comprise an optimal energy source and an important cell component. Researchers from the Biozentrum of the University of Basel and from the University of Geneva have now discovered that the protein mTOR stimulates the ...
Dec 11, 2017
0
4
A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) identifies potential new therapeutic avenues for patients with Alagille syndrome. The discovery, published in Nature Communications, ...
Oct 18, 2017
0
27
Exposure during infancy to the common plasticizer bisphenol A (BPA) "hijacks" and reprograms genes in the liver of newborn rats, leading to nonalcoholic fatty liver disease (NAFLD) in adulthood. A new study has found how ...
Apr 2, 2017
0
4
The liver is crucial for the detoxification of the human body. The exposure to toxins makes it particularly prone to drug-induced injury. Cholestasis, the impairment of bile flow, is therefore a common problem of drug development ...
Mar 27, 2017
0
26
