Diseases, Conditions, Syndromes

In acetaminophen-induced acute liver failure, FABP1 IDs mortality

(HealthDay)—Serum liver-type fatty acid binding protein (FABP1) early (day one) or late (day three to five) levels are associated with mortality in patients with acetaminophen (APAP)-induced acute liver failure (ALF), according ...

Diseases, Conditions, Syndromes

Fatty liver: Turning off TAZ reverses disease

Scientists at Columbia University Medical Center (CUMC) have identified a factor in liver cells that is responsible for turning a relatively benign liver condition, present in 30 percent of U.S. adults, into a serious disease ...

Diseases, Conditions, Syndromes

New medication shows promise against liver fibrosis in animal studies

A new drug developed by scientists at the National Institutes of Health limits the progression of liver fibrosis in mice, a hopeful advance against a condition for which there is no current treatment and that often leads ...

Diseases, Conditions, Syndromes

Gene therapy for metabolic liver diseases shows promise in pigs

With a shortage of donor organs, Mayo Clinic is exploring therapeutic strategies for patients with debilitating liver diseases. Researchers are testing a new approach to correct metabolic disorders without a whole organ transplant. ...

Genetics

New rapid gene test for mitochondrial disease

Newcastle researchers have developed a genetic test providing a rapid diagnosis of mitochondrial disorders to identify the first patients with inherited mutations in a new disease gene.

Medications

FDA approves ocaliva for primary biliary cholangitis

(HealthDay)—Ocaliva (obeticholic acid) has been approved by the U.S. Food and Drug Administration to treat primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adults with inadequate response ...

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