Diabetes

A single episode of high fat intake injures liver metabolism

Diets that are consistently high in saturated fat are linked to the development of non-alcoholic fatty liver disease and insulin resistance, but it's not clear how high fat foods initiate the changes that lead to disease.

Diseases, Conditions, Syndromes

Silencing fat protein improves obesity and blood sugar

In a study published in the Journal of Lipid Research, Saint Louis University scientist Angel Baldan, Ph.D., reports that turning off a protein found in liver and adipose tissue significantly improves blood sugar levels, ...

Overweight & Obesity

Researchers target gut bacteria to reduce weight gain

A new therapy that involves engineered gut bacteria may one day help reduce the health problems that come with obesity. Incorporating the engineered bacteria into the guts of mice both kept them from gaining weight and protected ...

Diseases, Conditions, Syndromes

New tool to identify persons with nonalcoholic fatty liver disease

Researchers have developed a diagnostic model that is highly predictive of nonalcoholic fatty liver disease (NAFLD). Referred to as the Framingham Steatosis Index (FSI), this novel model may become a cheaper and easier alternative ...

Medical research

How fat becomes lethal—even without weight gain

Sugar in the form of blood glucose provides essential energy for cells. When its usual dietary source—carbohydrates—is scarce, the liver can produce it with the aid of fat. But new research from Johns Hopkins now adds ...

Diseases, Conditions, Syndromes

Waist not weight—the key to non-alcoholic fatty liver disease

A new study presented today demonstrates that a build-up of fat around the waist can cause more serious complications than obesity in the development of non-alcoholic fatty liver disease (NAFLD). The study was presented at ...

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