Gene therapy that induces the body to create microRNA-22 (miR-22), a naturally occurring molecule, successfully treated mice with hepatocellular carcinoma, the most common form of liver cancer.
Aug 24, 2023
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The RNF41 protein could be a new therapeutic target in the fight against two chronic liver diseases: cirrhosis and liver inflammation. This is the conclusion of a study published in the journal Science Translational Medicine ...
Jul 28, 2023
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A mechanism underlying several liver diseases involves bile produced in the liver that cannot be secreted into the intestine as intended. This leads to a backlog of bile, which can damage the liver tissue.
Jul 3, 2023
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Yale researchers have found that liver fibrosis—scarring of the liver tissue that occurs in many chronic liver diseases—is associated with reduce cognitive ability and, in certain regions of the brain, reduced brain volume. ...
Jun 26, 2023
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New research is shedding light on global disparities in mortality rates from late-stage liver disease, also called cirrhosis. The study, published May 22 in The Lancet Gastroenterology & Hepatology, revealed that the risk ...
May 24, 2023
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Inflammatory fatty liver disease (NASH, non alcoholic steatohepatitis) and the resulting liver cancer are driven by auto-aggressive T cells. Scientists from the German Cancer Research Center (DKFZ) now show what is behind ...
May 23, 2023
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Researchers from Niigata University and Kyoto Prefectural University have revealed that small vesicles, around 100 nm in size, released by intestinal bacteria induce immune activation and progression of liver cirrhosis, as ...
Apr 19, 2023
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Macrophages are cells of the immune system that, in addition to playing an essential role in the early response to microbial infection, also regulate tissue function and inflammation. Inflammation is a physiological response ...
Feb 3, 2023
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A new study from researchers at Laval University in Quebec, Canada, shows that genetically increasing omega-3 fatty acid production, without direct gut microbiota contact, improves the balance of insulin and glucagon (glucose ...
Jan 25, 2023
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UT Southwestern immunologists have uncovered a key pathogenic event prompted by obesity that can trigger severe forms of nonalcoholic fatty liver disease and potential liver failure. The finding, published in Immunity, could ...
Dec 27, 2022
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