Medications
Circadian rhythms can influence drugs' effectiveness
Giving drugs at different times of day could significantly affect how they are metabolized in the liver, according to a new study from MIT.
Apr 24, 2024
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Page 24 - News tagged with liver metabolism
Oncology & Cancer
Study identifies a role for the metabolism regulator PPAR-gamma in liver cancer
Liver cancers are a major cause of cancer-related deaths. Large-scale genetic analyses have associated liver cancer with dysregulation of numerous molecular pathways, but disruptions in insulin signaling pathways appear to ...
Apr 10, 2017
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Medical research
In mice, mothers with metabolic syndrome can 'turn on' offspring's liver disease
New research from North Carolina State University has found that an imprinted gene associated with development of non-alcoholic fatty liver disease (NAFLD) is switched on in mice who nurse from mothers with metabolic syndrome, ...
Feb 7, 2022
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Diseases, Conditions, Syndromes
Increased fructose consumption may deplete cellular energy in patients with obesity and diabetes
Obese people who consume increased amounts of fructose, a type of sugar that is found in particular in soft drinks and fruit juices, are at risk for nonalcoholic fatty liver disease (NFALD) and more its more severe forms, ...
May 2, 2012
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Diseases, Conditions, Syndromes
Moderate and vigorous exercise have comparable effects on nonalcoholic fatty liver disease
A new study shows a brisk walk is just as good as a jog when it comes to reducing liver fatty content, important news for the more than 3 million people diagnosed each year in the U.S. with nonalcoholic fatty liver disease ...
Jul 6, 2016
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Diseases, Conditions, Syndromes
Causal relationship between adiposity and heart failure, and elevated liver enzymes
New evidence supports a causal relationship between adiposity and heart failure, and between adiposity and increased liver enzymes, according to a study published this week in PLOS Medicine. The study, conducted by Inga Prokopenko, ...
Jun 25, 2013
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Health
Perinatal exposure to flame retardant alters epigenome, predisposing metabolic disease
Studies have shown that perinatal exposure of rats and mice to common flame retardants found in household items permanently reprograms liver metabolism, often leading later in life to insulin resistance and non-alcoholic ...
Dec 13, 2019
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Diseases, Conditions, Syndromes
High fatty liver index tied to colorectal adenomas
(HealthDay)—The fatty liver index may be an accurate predictor of colorectal adenomas among an average-risk population, according to a study published in the January issue of Diseases of the Colon & Rectum.
Dec 18, 2017
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Medical research
Targeting autophagy to enhance memory immune responses
Memory B cells depend on autophagy for their survival, but the protein Rubicon is thought to hinder this process. Researchers from Osaka University have discovered a shorter isoform of Rubicon called RUBCN100, which enhances ...
Oct 2, 2023
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Diabetes
Ability to chart the molecular progress of diabetes brings personalized medicine closer to realization
Researchers in Singapore have succeeded in tracking, for the first time, the molecular changes caused by type 2 diabetes that affect how the body handles glucose production in the liver. In a series of experiments in mice, ...
Dec 19, 2012
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