Fatty liver, or hepatic steatosis, which develops when the body produces too much fat or doesn't metabolize fat efficiently enough, affects around 25% of the global population. Excess fat is stored in liver cells, where it ...
Dec 20, 2019
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Researchers from VIB-UGent Center for Medical Biotechnology, University of Iowa (USA) and other collaborators, developed a novel approach to better understand a basic defense mechanism of our immune system. Central is ISG15, ...
Nov 26, 2019
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Researchers have discovered that a key cell type involved in liver injury and cancer consists of two cellular families with different origins and functions.
Oct 15, 2019
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New findings show how a genetically aberrant, fused protein promotes a rare form of liver cancer in adolescents and young adults. The researchers also saw that a certain mix of drugs could target the fused protein and the ...
Jul 9, 2019
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Researchers from Karolinska Institutet in Sweden have found a protein that is a critical regulator in the development of fatty liver disease in mice, according to a study published in the journal Nature Communications.
Apr 11, 2019
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An attractive approach to liver cancer treatment is to bolster the body's own immune defenses. Now an international team involving A*STAR researchers has genetically engineered human T cells to endow them with both specificity ...
Mar 18, 2019
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One in four people in Western and Asian societies develop a build-up of fat in the liver as a result of an unhealthy diet. This disease – referred to as non-alcoholic fatty liver disease (NAFLD) – causes no symptoms initially ...
Mar 1, 2019
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Mutations in RAS proteins initiate many of the most aggressive tumors, and the search for pharmacological inhibitors of these proteins has become a priority in the battle against cancer. Michail Steklov, Francesca Baietti, ...
Nov 16, 2018
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Small chemical changes in the DNA building blocks, which may be influenced by lifestyle factors, can reduce the amount of IGFBP2. A DIfE / DZD research team has now reported in the journal Diabetes that these epigenetic changes ...
Nov 9, 2018
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Chronic excessive caloric intake leads to the deposition of fat droplets in the liver. This condition, known as fatty liver, can cause permanent damage to the organ. Researchers at the Max Planck Institute of Biochemistry ...
Oct 26, 2018
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