Medical research

Blood holds key to liver regeneration

The liver is the only organ in the body that can regenerate. But some patients who undergo a liver resection, a surgery that removes a diseased portion of the organ, end up needing a transplant because the renewal process ...

Diseases, Conditions, Syndromes

New regulator for liver regeneration

By performing large-scale proteomics analysis of liver proteins, ETH researchers have discovered a protein that is essential for liver regeneration. They have also figured out the mechanism of the protein's function.

Diseases, Conditions, Syndromes

Scientists have found a new mechanism for the liver cell regeneration

An international research collaborative has demonstrated for the first time the role of cholangiocytes (epithelial bile duct cells) in liver regeneration. The results of the study are highly promising for regenerative medicine ...

Medical research

Engineered liver tissue expands after transplant

Many diseases, including cirrhosis and hepatitis, can lead to liver failure. More than 17,000 Americans suffering from these diseases are now waiting for liver transplants, but significantly fewer livers are available.

Diseases, Conditions, Syndromes

p53 critical to recovering from acetaminophen overdose

Results from a new study show that after an acetaminophen overdose the p53 protein plays a key role in preventing the progression of liver damage and signaling the liver to repair itself. The findings could lead to new treatments ...

Genetics

Scientists reveal endocardial origin of liver vasculature

On March 29, Nature Genetics published a research article titled "Genetic lineage tracing identifies endocardial origin of liver vasculature," from Prof. ZHOU Bin's lab at the Institute for Nutritional Sciences (INS), Shanghai ...

Medical research

Protein may improve liver regeneration

Researchers at UC Davis have illuminated an important distinction between mice and humans: how human livers heal. The difference centers on a protein called PPARĪ±, which activates liver regeneration. Normally, mouse PPARĪ± ...

Diseases, Conditions, Syndromes

New genetic link found for alcohol-related liver cirrhosis

In most people, any liver damage that might occur from drinking alcohol is reversible. However, in 25 to 30 percent of alcoholics what begins as accumulation of fat in the liver progresses to inflammation, fibrosis and ultimately ...

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