A breakthrough in the understanding of the relationship between a naturally occurring enzyme and the liver cancer drug sorafenib could improve the effectiveness of the drug, which currently prolongs the life of liver cancer ...
Dec 4, 2023
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The most socioeconomically deprived groups in society are nearly twice as likely to die from sepsis within 30 days, researchers from The University of Manchester have found.
Nov 23, 2023
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Cell and organ transplants can be lifesaving, but patients often encounter long waiting lists due to the shortage of suitable donors. According to donatelife.net, in 2021, 6,000 people died in the U.S. alone while waiting ...
Nov 22, 2023
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Gene therapy has great promise for treating genetic diseases, and even for more common diseases such as atherosclerosis (hardening of the arteries). Over the past decade, the gene-editing technology CRISPR (Clustered Regularly ...
Nov 16, 2023
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Cannabidiol (CBD) is marketed by some suppliers as a painkiller, e.g., for osteoarthritis of the knee. Animal experiments have shown that the substance, which is extracted from the hemp plant, has an anti-inflammatory and ...
Nov 14, 2023
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Looking around us, we can see that people age at different rates. But what about inside? Do all cells age in the same way? And does the location of a cell in the organ make a difference to the aging process?
Nov 10, 2023
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An international clinical trial involving Birmingham Professor Phil Newsome identified a promising target for patients with non-alcoholic steatohepatitis (NASH), as reported in a paper published yesterday (Nov. 6) in Nature ...
Nov 7, 2023
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Gene therapy adeno-associated viruses (AAVs)—viruses that can be engineered to deliver DNA to target cells—are unlikely to cause cancer-triggering insertions in humans or monkeys and may contribute to long-term efficacy, ...
Nov 6, 2023
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Phenylketonuria (PKU) is a rare newborn genetic disease that impacts between 1 in 10,000 to 1 in 20,000 people, depending on the individuals' genetic ancestry. PKU causes an amino acid—called phenylalanine (Phe)—to build ...
Nov 2, 2023
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An international study involving Birmingham researchers identified for the first time how a protein found in the endothelium supports the transfer of specific immune cells, called macrophages, from the blood into the liver, ...
Oct 30, 2023
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