Immunology

'Cell food' gives insight into T cell metabolism

New research from the University of Michigan Rogel Cancer Center reveals that the metabolic pathways that make a specific type of T cell function are different than previously believed. The key to this discovery lies in a ...

Diabetes

Diabetes: When circadian lipid rhythms go wrong

Like all living beings, human physiological processes are influenced by circadian rhythms. The disruption of our internal clocks due to an increasingly unbalanced lifestyle is directly linked to the explosion in cases of ...

Genetics

A single gene can disrupt the sleep-wake cycle

All living organisms are subject to an internal biological rhythm, which controls many physiological processes. In humans in particular, this internal clock follows a 24-hour cycle and occurs even in the absence of external ...

Medical research

Common tumor inhibitor drug triggers unfavorable immune effects

Cancer immunotherapy involving drugs that inhibit CTLA-4 also activates an unwanted response that may self-limit its efficacy in fighting tumors, according to a new study led by Francesco Marangoni, Ph.D., assistant professor ...

Medical research

Generation of three-dimensional heart organoids

Researchers from Tokyo Medical and Dental University (TMDU) use mouse embryonic stem cells to engineer three-dimensional functional heart organoids resembling the developing heart

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