Cardiology

Evinacumab cuts cholesterol levels by half in patients with HoFH

The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol to near-normal levels among patients with a rare cholesterol disorder, meeting the primary endpoint in the first randomized placebo-controlled ...

Medical research

Using mice to explore the prevention of blocked arteries

It's long been known that a high-fat diet can lead to clogged arteries, but we have only recently begun to learn in detail how the process works. A new study in experimental mice could go a long way to finding treatments ...

Overweight & Obesity

Childhood obesity prevention programs impact LDL-C, HDL-C

(HealthDay)—Childhood obesity prevention programs are beneficial for low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C), according to a systematic review and meta-analysis published ...

Cardiology

Fish oil supplementation tied to lower atherothrombotic risk

(HealthDay)—Fish oil supplementation (FOS) is associated with atherothrombotic risk reduction in suspected coronary artery disease (sCAD), according to a study published in the May 1 issue of The American Journal of Cardiology.

Medications

Lomitapide in hypercholesterolaemia: No hint of added benefit

Lomitapide (trade name: Lojuxta) has been available since July 2013 as additional treatment for adults with homozygous familial hypercholesterolaemia in whom diet and other drugs do not sufficiently lower cholesterol levels. ...

Cardiology

High LDL in young, healthy adults leaves them vulnerable to CVD

(HealthDay)—Low-density lipoprotein cholesterol (LDL-C) and non-high density lipoprotein cholesterol (non-HDL-C) ≥160 mg/dL are independently associated with increased relative risk of cardiovascular disease (CVD) mortality ...

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