Adenocarcinoma histology, female sex, never-smoking status, and Asian ethnicity have been considered the most important factors associated with EGFR mutations in non-small cell lung cancer and response to EGFR inhibitors. ...
Feb 15, 2014
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Research from the National Institute of Respiratory Diseases (INER) reveals that besides smoking, there are other factors associated with the development of lung cancer such as the smoke from burning lumber and coal, as well ...
Jan 7, 2014
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A fine-grained scan of DNA in lung cancer cells has revealed a gene fusion – a forced merger of two normally separate genes – that spurs the cells to divide rapidly, scientists at Dana-Farber Cancer Institute and the ...
Oct 28, 2013
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A protein called isocitrate dehydrogenase (IDH1) is present at high levels in lung cancers and can be detected in the blood, making it a noninvasive diagnostic marker for lung cancers, according to a study published in Clinical ...
Sep 17, 2013
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(Medical Xpress)—Two University of Colorado Cancer Center publications set stage for K9 cancer vaccine test with human glioblastoma. Michael Graner, PhD, is a CU Cancer Center investigator and associate professor of neurosurgery ...
Jun 27, 2013
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ALK rearrangement has been demonstrated to be a potent oncogenic driver and a promising therapeutic target in non-small cell lung cancer (NSCLC). It defines a distinct molecular subset of NSCLC, in particular adenocarcinoma ...
Jun 25, 2013
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(HealthDay)—A case of acquired resistance to crizotinib has been described in a patient with metastatic lung adenocarcinoma harboring a CD74-ROS1 rearrangement, according to a brief report published online June 1 in the ...
Jun 3, 2013
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In results presented at ASCO 2013, a University of Colorado Cancer Center study provides important details for a recently identified driver and target in lung adenocarcinoma: rearrangement of the gene RET. The finding is ...
Jun 3, 2013
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A new drug can help advanced lung cancer patients live longer and may aid in treating other kinds of cancer, researchers said Monday.
Jun 3, 2013
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The identification of potentially targetable kinase mutations has been an exciting advancement in lung cancer treatment. Although the mutations driving many lung carcinomas remain unknown, approximately 50 percent of lung ...
Apr 22, 2013
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