The new drug sotorasib reduces tumor size and shows promise in improving survival among patients with lung tumors caused by a specific DNA mutation, according to results of a global phase 2 clinical trial. The drug is designed ...
Jun 4, 2021
0
41
A new cancer vaccine could boost the positive effects of existing immunotherapy drugs, improving the success rate of treatments from 20% to 75% of cases, according to a new study by immunologists from the University of Konstanz. ...
May 18, 2021
0
218
A phase 1 clinical trial led by investigators at the University of Chicago Medicine testing the effects of stereotactic body radiotherapy for treating multiple metastases has determined that treatments used for single tumors ...
Apr 22, 2021
0
57
Using samples of small cell lung tumors, a research team led by biologist Dr. Silvia von Karstedt has discovered two new ways to induce tumor cell death. One of two subsets of tumor cells can be targeted by activating ferroptosis: ...
Apr 6, 2021
0
75
Cancers are not only made of tumor cells. In fact, as they grow, they develop an entire cellular ecosystem within and around them. This "tumor microenvironment" is made up of multiple cell types, including cells of the immune ...
Mar 22, 2021
0
215
The first randomized Phase II clinical trial to report on single and combined neoadjuvant immune checkpoint inhibitor therapy in stage I-III non-small cell lung cancer (NSCLC) found combination therapy produced a significant ...
Feb 18, 2021
0
27
Michael Green, M.D., Ph.D., noticed that when his patients had cancer that spread to the liver, they fared poorly—more so than when cancer spread to other parts of the body. Not only that, but transformative immunotherapy ...
Jan 4, 2021
0
156
Scientists have long known that therapies that target the cancer-driving MAPK pathway are only effective in a handful of cancers with specific mutations in a cancer gene called BRAF, and these cancers that initially respond ...
Dec 14, 2020
0
78
A research team led by experts at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center reports favorable five-year survival rates from the first multidose clinical trial of the ...
Jul 25, 2019
2
1276
Some patients with breast cancer receive chemotherapy before the tumor is removed with surgery. This approach, called neoadjuvant therapy, helps to reduce the size of the tumor to facilitate breast-conserving surgery, and ...
Jan 2, 2019
0
482
