Scientists studying cancer development have known about micronuclei for some time. These erratic, small extra nuclei, which contain fragments, or whole chromosomes that were not incorporated into daughter cells after cell ...
Jul 9, 2013
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For the first time, researchers describe the genetic program behind primordial lung progenitors—embryonic cells that give rise to all the cells that form the lining of the respiratory system after birth. They believe this ...
Jan 31, 2020
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Using CRISPR gene editing, a team from Children's Hospital of Philadelphia (CHOP) and Penn Medicine have thwarted a lethal lung disease in an animal model in which a harmful mutation causes death within hours after birth. ...
Apr 17, 2019
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Scientists have coaxed stem cells to grow the first three-dimensional mini lungs.
Mar 24, 2015
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Drugs that target specific proteins have greatly improved patient outcomes across a broad range of tumor types; however, patients often develop drug resistance and tumor recurrence. There is a great unmet need to identify ...
Jul 29, 2021
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Specialized lung cells appear in the developing fetus much earlier than scientists previously thought. A new animal study published this week in the Proceedings of the National Academy of Sciences reports how cells that become ...
Feb 18, 2019
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Very premature babies need extra oxygen and mechanical intervention to breathe, but this damages their lungs, causing a chronic lung disease called bronchopulmonary dysplasia (BPD). These babies have smaller and weaker lungs ...
Mar 30, 2022
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Researchers at the University of Virginia School of Medicine have discovered a flaw in the armor of the most aggressive form of lung cancer, a weakness that doctors may be able to exploit to slow or even stop the disease. ...
Aug 17, 2016
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Most cells can divide only a limited number of times and eventually undergo permanent cell cycle arrest, a state known as cellular senescence. Cellular senescence is mediated by activation of specific cellular signaling pathways ...
Aug 4, 2016
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A research team led by Fred Hutchinson Cancer Research Center has discovered proteins in the blood that are associated with early lung cancer development in mice and humans. The advance brings the reality of a blood test ...
Sep 12, 2011
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