Inflammatory disorders

DNA-modulating drug attenuates lung inflammation in mice

Patients with cystic fibrosis (CF) suffer from chronic respiratory infections, primarily caused by Pseudomonas aeruginosa, which lead to airway inflammation and damage. Several recent studies have suggested that a specific ...

Medical research

Progression of lung fibrosis blocked in mouse model

A study by researchers at the University of California, San Diego School of Medicine may lead to a way to prevent the progression, or induce the regression, of lung injury that results from use of the anti-cancer chemotherapy ...

Diseases, Conditions, Syndromes

Long-term inhaled dry powder mannitol improves lung function in CF

Adding inhaled dry powder mannitol to standard therapy for cystic fibrosis produced sustained improvement in lung function for up to 52 weeks, according to a new study. Along with the treatment's efficacy and good safety ...

Diseases, Conditions, Syndromes

HRCT scans can identify deadly lung disease

People who have suspected idiopathic pulmonary fibrosis (IPF) without typical patterns on high resolution computed tomography scans could in future be spared the substantial risks of lung biopsy and be given a confident diagnosis ...

Medications

Triple-combination therapy helps more people with cystic fibrosis

Researchers at National Jewish Health and around the world report today that a three-drug combination of medications can improve lung function, reduce exacerbations and improve quality of life for people with cystic fibrosis ...

Medical research

Five genetic regions implicated in cystic fibrosis severity

If you have two faulty copies of the CFTR gene, you will have cystic fibrosis. But the severity of your disease will depend on environmental factors and many other genes. Locating these genes and altering their function could ...

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