Diseases, Conditions, Syndromes

Silicosis is on the rise, but is there a therapeutic target?

Researchers from the CNRS, the University of Orléans, and the company Artimmune, in collaboration with Turkish clinicians from Atatürk University, have identified a key mechanism of lung inflammation induced by silica exposure, ...

Immunology

A deeper look at severe asthma yields NET results

Of the more than 24 million people in the U.S. who have asthma, 10 percent have severe asthma—a form of the disease that does not respond to treatment. The immunological mechanisms underlying severe asthma and asthmatic ...

Immunology

Why do more women have asthma than men? Blame hormones

Women are twice as likely as men to have asthma, and this gender difference may be caused by the effects of sex hormones on lung cells. Researchers at Vanderbilt University and Johns Hopkins found that testosterone hindered ...

Inflammatory disorders

Experimental drug targets nucleus of allergen-sensitized cells

Transcription factors, the tiny proteins that switch genes on or off in the nucleus of cells, are considered unreachable molecular targets for drugs attempting to treat medical conditions. Overcoming this challenge, researchers ...

Oncology & Cancer

Lung inflammation contributes to metastasis

Pre-existing inflammation in the lungs may increase the risk that cancers beginning elsewhere will spread to that organ, according to new research from Weill Cornell Medicine.

Neuroscience

Targeting nerve endings to curb allergic asthma

Current asthma medications, which work by suppressing inflammatory signaling by immune cells or by dilating the airways, can stop working over time. A study from Boston Children's Hospital, Brigham and Women's Hospital, and ...

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