Researchers from Weill Cornell Medicine have used human embryonic stem cells to create a new model system that allows them to study the initiation and progression of small cell lung cancer (SCLC). The study, which will be ...
Feb 8, 2019
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MIT cancer biologists have discovered a new mechanism that lung tumors exploit to promote their own survival: These tumors alter bacterial populations within the lung, provoking the immune system to create an inflammatory ...
Jan 31, 2019
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In an article recently published in JCI Insight, researchers from the University of Alabama at Birmingham and Vanderbilt University have identified checkpoint inhibitor resistance mechanisms in many solid tumor cancers, including ...
Jan 23, 2019
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A Ludwig Cancer Research study has uncovered a cellular mechanism by which melanomas that fail to respond to checkpoint blockade may be made susceptible to immunotherapies. Led by Ping-Chih Ho of the Lausanne Branch of the ...
Jan 23, 2019
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Immunotherapies that take off the "brakes" on the adaptive anti-tumor response have worked well in melanoma and lung cancer but less so in breast cancers. That could change.
Jan 17, 2019
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Pharmaceutical giant Eli Lilly announced Monday it will acquire Loxo Oncology for around $8 billion, the latest big transaction aimed at developing and monetizing new treatments for cancer.
Jan 7, 2019
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A new mechanism for activating the immune system against cancer cells allows immune cells to detect and destroy cancer cells better than before, according to a study published this week in the journal Nature.
Jan 4, 2019
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Some patients with breast cancer receive chemotherapy before the tumor is removed with surgery. This approach, called neoadjuvant therapy, helps to reduce the size of the tumor to facilitate breast-conserving surgery, and ...
Jan 2, 2019
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The CRISPR-Cas9 gene editing system may be able to restore the effectiveness of first-line chemotherapies used to treat lung cancer by deleting or "knocking out" a gene in cancer tumors that helps the tumors develop resistance ...
Dec 17, 2018
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Researchers at The University of Texas MD Anderson Cancer Center have identified a link between an enzyme tied to cancer formation and therapy resistance in patients with epidermal growth factor receptor (EGFR)-mutant non-small ...
Dec 10, 2018
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