Immunology

Lupus strongly linked to imbalances in gut microbiome

The disease systemic lupus erythematosus (SLE)—marked by the attack on joints, skin, and kidneys by the body's immune system—is linked to an abnormal mix of bacteria in the gut. This is according to a new study led by ...

Diseases, Conditions, Syndromes

Possible treatment for kidney disease in lupus studied at UH

In the U.S. alone, more than 1.5 million people have lupus, a chronic autoimmune disease in which the immune system turns against itself, attacking a person's healthy tissue, cells and organs. The symptoms can range from ...

Arthritis & Rheumatism

Exercise training improves cardiac parameters in lupus

(HealthDay) -- For inactive patients with systemic lupus erythematosus (SLE), a three-month exercise training program is associated with improved chronotropic reserve and heart rate recovery, according to a study published ...

Arthritis & Rheumatism

Anifrolumab shows long-term promise in patients with lupus

Type I interferon (IFN) is a powerful immune activator that is present at high levels in the majority of patients with lupus, an autoimmune disease. In Arthritis & Rheumatology, researchers report positive results from the ...

Arthritis & Rheumatism

World's first CAR-T cell therapy for a child with lupus

In June 2023, Uresa A. (who was 15 years old at the time) received CAR-T cells at Universitätsklinikum Erlangen. The treatment was the last resort to slow down systemic lupus erythematosus (SLE), which is a serious autoimmune ...

Diseases, Conditions, Syndromes

New test could give SLE patients a more tolerable life

Five million people worldwide suffer from the chronic rheumatic disease SLE, systemic lupus erythematosus. Together with rheumatologists, researchers at Lund University in Sweden are on the way to developing a new test that ...

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