Diseases, Conditions, Syndromes

What makes an mRNA vaccine so effective against severe COVID-19?

The first two vaccines created with mRNA vaccine technology—the Pfizer/BioNTech and Moderna COVID-19 vaccines—are arguably two of the most effective COVID vaccines developed to date. In clinical trials, both were more ...

Oncology & Cancer

Talk between immune cells could lead to new cancer vaccine

In the past decade, immunotherapy has helped save the lives of many cancer patients, many with lung cancer, who might have otherwise faced almost certain death sentences. However, only about 20% of patients who received immune ...

Oncology & Cancer

Cancer registry improves understanding of rare ovarian tumor

Ovarian granulosa cell tumors are a rare type of ovarian cancer that affect the ovaries and fallopian tubes, and can extend further into the pelvis and lymph nodes. Treatment typically follows the same guidelines as other ...

Oncology & Cancer

GABA released by B-cells blunts the immune response to tumors

A group of scientists led by researchers from the RIKEN Center for Integrative Medical Sciences have discovered that B-cells, a type of immune cell, secrete the neurotransmitter GABA, and also found that the GABA secreted ...

Alzheimer's disease & dementia

Trial begins of nasal vaccine for Alzheimer's disease

(HealthDay)—The first human clinical trial of a nasal vaccine to slow the progression of Alzheimer's disease is set to begin after nearly 20 years of research.

Immunology

Bone marrow backup needed to tackle respiratory infections

Scientists at the Francis Crick Institute have found how the immune system triggers an 'emergency' dendritic cell response during infection, with dendritic cells at the site of infection being reinforced by new cells which ...

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