Genetics

Multiple sclerosis as the flip side of immune fitness

About half of the people with multiple sclerosis have the HLA-DR15 gene variant. A study led by the University of Zurich has now shown how this genetic predisposition contributes to the development of the autoimmune disease ...

Immunology

'Multi-omics' adds new cell to immune family tree

WEHI researchers have used powerful 'single cell multi-omics' technologies to discover a previously unknown ancestor of T and B lymphocytes, which are critical components of our immune system.

Cardiology

T cells can shift from helping to harming in atherosclerosis

High cholesterol kills. In fact, one in four Americans will die from the consequences of atherosclerosis, the buildup of plaques of fat and cholesterol in the arteries. Statins have helped reduce mortality, but millions are ...

Immunology

B cells and their function in the immune system

Whenever a germ gets into the human body, the immune system usually responds immediately to fight off the enemy attacker. One of our defense system's most important strategies involves B lymphocytes, also known as B cells, ...

Oncology & Cancer

Immune cells hampered when fighting soft tissue and bone sarcomas

Aggregates of immune cells known as tertiary lymphoid structures (TLSs), seen here within a tumor of the soft tissues known as a rhabdomyosarcoma, are major players in the immune system's fight against cancer. Johns Hopkins ...

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Lymphocyte

A lymphocyte is a type of white blood cell in the vertebrate immune system.

Under the microscope, lymphocytes can be divided into large lymphocytes and small lymphocytes. Large granular lymphocytes include natural killer cells (NK cells). Small lymphocytes consist of T cells and B cells.

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