Medical research

New models advance the study of deadly human prion diseases

By directly manipulating a portion of the prion protein-coding gene, Whitehead Institute researchers have created mouse models of two neurodegenerative diseases that are fatal in humans. The highly accurate reproduction of ...

Medical research

The flexible tail of the prion protein poisons brain cells

For decades, there has been no answer to the question of why the altered prion protein is poisonous to brain cells. Neuropathologists from the University of Zurich and University Hospital Zurich have now shown that it is ...

Medical research

New yeast prion helps cells survive

One of the greatest mysterious in cellular biology has been given a new twist thanks to findings reported in Science. Researchers at the RIKEN Brain Science Institute show that prions, proteins that transmit heritable information ...

Diseases, Conditions, Syndromes

Blood test for human form of mad cow disease developed

(Medical Xpress) -- Mad cow disease is serious business in the U.K., the human form, known as Creutzfeldt-Jakob after Hans Gerhard Creutzfeldt and Alfons Maria Jakob (CJD), who independently first described its existence ...

Neuroscience

Fertility and prion disease

A high degree of uncertainty surrounds the issue of the prion disease risk associated with fertility drugs derived from urine, gonadotropins. Writing in the International Journal of Risk Assessment and Management, a team ...

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