A new chimeric antigen receptor (CAR) T-cell product had an acceptable safety profile and showed early signs of efficacy as a monotherapy and in combination with an mRNA vaccine in patients with solid tumors, according to ...
Apr 10, 2022
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Researchers at Koç University discovered why a promising class of cancer treatments fail, and their findings point to how such treatments might be made to work. The research revealed the mechanisms behind the development ...
Jan 28, 2022
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Doctors and scientists from the German Cancer Research Center (DKFZ) and from Heidelberg University's Medical Faculty Mannheim have successfully tested a neoantigen-specific transgenic immune cell therapy for malignant brain ...
Nov 15, 2021
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The PrE0505 phase 2 clinical trial results are published in the November 8 issue of Nature Medicine. The study evaluated the addition of durvalumab immunotherapy to standard chemotherapy in patients with previously untreated, ...
Nov 8, 2021
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Cancerous tumors are made up of many more components than just malignant cells from the tissue of origin. Immune cells can be recruited to the tumor site and form what is known as the tumor microenvironment. A subset of these ...
Oct 18, 2021
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A group of researchers has created nanomachines that detect MMPs (matrix metalloproteinases), a principal enzyme for cancer cells to invade normal tissue, and deliver anticancer drugs according to an announcement in the journal ...
Oct 12, 2021
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Findings from a national study by researchers at Translational Genomics Research Institute (TGen), an affiliate of City of Hope, and external collaborators suggest that sex and age are crucial factors in the care and survival ...
Sep 22, 2021
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The latest special issue of PLOS Medicine features five studies outlining novel strategies for detecting cancer and for identifying minimal residual disease—when a small amount of tumor cells survive treatment, potentially ...
Aug 31, 2021
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A new study found that incidence rates for malignant brain and other central nervous system (CNS) tumors declined by 0.8% annually during 2008 through 2017 in the United States for all ages combined. The decline was driven ...
Aug 24, 2021
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Magnetic resonance imaging (MRI) is widely used in medicine to detect, diagnose and treat diseases such as cancer, while relying on experts' interpretation of images. Quantitative MRI, which obtains numerical measurements ...
Jun 30, 2021
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