Some patients with breast cancer receive chemotherapy before the tumor is removed with surgery. This approach, called neoadjuvant therapy, helps to reduce the size of the tumor to facilitate breast-conserving surgery, and ...
Jan 2, 2019
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Scientists have long known that cancer can hijack a cell's existing regulatory circuitry and transform healthy cells into deadly malignancies. But a new discovery from UC San Francisco demonstrates that cancer is more than ...
Nov 8, 2018
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Researchers have discovered that normal breast development relies on a genetic 'brake', a protein complex that keeps swathes of genes silenced.
Aug 17, 2018
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Researchers at the Princess Margaret Cancer Centre in Toronto have discovered that epigenetic proteins promote the proliferation of mammary gland stem cells in response to the sex hormone progesterone. The study, which will ...
Jun 19, 2018
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Rare stem-like tumor cells play a critical role in the spread of breast cancer, but a vulnerability in the pathway that powers them offers a strategy to target these cells using existing drugs before metastatic disease occurs, ...
Dec 12, 2017
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Substantial advancements have improved the success of chemotherapy, radiation, and surgical treatments for primary breast cancers. However, breast cancer that has spread, or metastasized, to other parts of the body remains ...
Dec 11, 2017
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Breast cancer researchers have mapped early genetic alterations in normal-looking cells at various distances from primary tumours to show how changes along the lining of mammary ducts can lead to disease.
Nov 1, 2017
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One of the key questions in stem cell and cancer biology is to understand the cellular hierarchy governing tissue development and maintenance and the cancer cell of origin. In a study published in Cell Reports, researchers ...
Aug 16, 2017
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Cancer of the mammary glands in dogs is very similar to human breast carcinoma. For this reason, treatment methods from human medicine are often used for dogs. Conversely, scientific knowledge gained from canine mammary tumors ...
Jun 6, 2017
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For years, cancer experts have realized that cancerous cells behave in certain ways like stem cells, unspecialized cells that when exposed to certain signals, can "differentiate."
Jun 1, 2017
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