Medical research

Mammary stem cells challenge costly bovine disease

Mastitis is the most expensive disease in the dairy industry. Each clinical case can cost a dairy farmer more than $400 and damages both the cow's future output as well as her comfort.

Oncology & Cancer

Drug suppresses spread of breast cancer caused by stem-like cells

Rare stem-like tumor cells play a critical role in the spread of breast cancer, but a vulnerability in the pathway that powers them offers a strategy to target these cells using existing drugs before metastatic disease occurs, ...

Oncology & Cancer

PUMA pathway is a weak link in breast cancer metastasis

Substantial advancements have improved the success of chemotherapy, radiation, and surgical treatments for primary breast cancers. However, breast cancer that has spread, or metastasized, to other parts of the body remains ...

Oncology & Cancer

Metastatic breast cancer cells turn on stem cell genes

It only takes seconds: one cancerous cell breaks off from a tumor, slips into the bloodstream and quickly lodges elsewhere in the body. These colonizers may bloom into deadly metastatic cancer right away or lie dormant for ...

Oncology & Cancer

Variations in cell programs control cancer and normal stem cells

In the breast, cancer stem cells and normal stem cells can arise from different cell types but tap into distinct yet related stem cell programs, according to Whitehead Institute researchers. The differences between these ...

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