Oncology & Cancer

Genomic markers of aggressive childhood leukemias identified

New research published today in JAMA Oncology reports how two separate DNA changes appear to predict aggressive childhood leukemias when they occur in combination. Over the course of a decade of work in several study sites ...

Medical research

High blood sugar levels 'reprogram' stem cells

High levels of glucose in the blood "reprogrames" stem cells, leading to a lasting increase in the risk of developing dangerous atherosclerosis, according to research funded by the British Heart Foundation published today ...

Oncology & Cancer

Sensing 'junk' RNA after chemotherapy enhances blood regeneration

Chemotherapy is widely used to treat cancer patients. During the treatment, chemotherapeutic agents affect various biochemical processes to kill or reduce the growth of cancer cells, which divide uncontrollably in patients. ...

Surgery

Mayo Clinic: Why bone marrow donor diversity is needed

Bone marrow transplants are procedures that infuse healthy blood stem cells into your body to replace damaged or diseased bone marrow. Just like people in need of solid organ transplants, such as hearts or kidneys, people ...

Oncology & Cancer

Blood stem cells make brain tumors more aggressive

For the first time, scientists from the German Cancer Consortium (DKTK) partner site in Essen/Düsseldorf have discovered stem cells of the hematopoietic system in glioblastomas, the most aggressive form of brain tumor. These ...

Immunology

Improving bone marrow transplants in mice to help fight disease

To study the immune system in human health and disease, scientists commonly use the genetic manipulation of mouse hematopoietic stem and progenitor cells (HSPCs) as a powerful model system. These studies have been extremely ...

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