Medical research

Uncovering secrets of bone marrow cells and how they differentiate

Bone marrow contains biological factories, which pump out billions of new blood cells daily. The non-blood cells that maintain this production also have the potential to produce bone, fat and cartilage. This output all starts ...

Medical research

New genetic weapons challenge sickle cell disease

Help for patients with sickle cell disease may soon come from gene editing to fix the mutation that causes the disease and boost the patient's own protective fetal hemoglobin.

Oncology & Cancer

An atlas of an aggressive leukemia

A team of researchers led by Bradley Bernstein at the Ludwig Center at Harvard has used single-cell technologies and machine learning to create a detailed "atlas of cell states" for acute myeloid leukemia (AML) that could ...

Medical research

Scientists generate functional, transplantable B cells from mice

Functional B-1 cells derived from mouse embryonic stem cells are capable of long-term engraftment and secrete natural antibodies after transplantation in mice, researchers report February 7th in the journal Stem Cell Reports. ...

Medical research

Scientists have identified a bone marrow backup system

New research from the Stowers Institute for Medical Research has identified the backup for an important biological system—the hematopoietic system, whose adult stem cells constantly replenish the body's blood supply.

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