Medical research

Scientists identify pivotal cellular protein underlying eczema

Researchers from the La Jolla Institute for Allergy and Immunology have revealed a critical player in the cellular interactions leading to eczema – a chronic inflammatory skin condition affecting more than 14 million U.S. ...

Immunology

Salmonella jams signals from bacteria-fighting mast cells

A protein in Salmonella inactivates mast cells—critical players in the body's fight against bacteria and other pathogens—rendering them unable to protect against bacterial spread in the body, according to researchers ...

Medical research

Staph infections and eczema: What's the connection?

For the millions of people suffering from the intensely red, horribly itchy skin condition known as eczema, the only thing more maddening than their disease is the lack of understanding of what causes it, or makes it flare ...

Oncology & Cancer

Targeted cancer treatment: Cause of skin infections identified

Targeted, successful cancer treatments are very often accompanied by unpleasant side effects. Especially in anti-EGFR treatments the skin is often so badly affected by inflammations that patients consider breaking off the ...

Diseases, Conditions, Syndromes

Mast cells give clues in diagnosis, treatment of dengue

A protein produced by mast cells in the immune system may predict which people infected with dengue virus will develop life-threatening complications, according to researchers at Duke Medicine and Duke-National University ...

Medical research

Mast cells have critical role in initializing pulmonary fibrosis

Pulmonary fibrosis is a chronic, deadly disease that affects five million people worldwide. It is irreversible, its cause is poorly understood, and it has a median survival of only about 3 years. A new study that implicates ...

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