Many melanoma patients are treated with drugs called BRAF or MEK inhibitors that specifically target the mutant proteins created in cancerous tumors. These inhibitors can block the tumors' ability to grow and spread.
Feb 28, 2022
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Immunotherapy, which harnesses the power of the body's immune system to fight disease, is gaining huge traction in treating cancer. Chief among cancer immunotherapies is a treatment known as CAR-T, or chimeric antigen receptor ...
Oct 4, 2021
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In the progressing field of immunotherapy, surprisingly little is known about immunity to metastatic tumors in locations such as lymph nodes, a frequent place where cancers first spread. Not only do lymph nodes act as a gateway ...
Sep 14, 2021
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An immunotherapy based on supercharging the immune system's natural killer cells has been effective in treating patients with recurrent leukemia and other difficult to treat blood cancers. Now, researchers at Washington University ...
Jun 29, 2021
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A dysfunctional immune system significantly contributes to the development of cancer. Several therapeutic strategies to activate the immune system to target cancer cells have been approved to treat different types of cancer, ...
Apr 8, 2021
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Some melanoma patients respond very well to immunotherapy, experiencing profound and durable tumor regression. A fraction of these patients will also develop autoimmunity against their normal melanocytes—the cells that ...
Mar 24, 2021
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Four years after patients with melanoma were treated with a personalized cancer vaccine, the immune response kindled by the vaccine remains robust and effective in keeping cancer cells under control, researchers at Dana-Farber ...
Jan 21, 2021
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Scientists at The Wistar Institute have created an advanced humanized immune system mouse model that allows them to examine resistance to immune checkpoint blockade therapies in melanoma. It has revealed a central role for ...
Jan 12, 2021
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In their move to circumvent the immune system, melanoma cells end up with a deficiency of the crucial nutrient tryptophan. Unlike healthy cells, these cancer cells can continue to synthesize proteins to survive, but this ...
Dec 17, 2020
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Research led by Queen Mary University of London has revealed novel insights into the mechanisms employed by melanoma cells to form tumors at secondary sites around the body. The findings from the study may help to identify ...
Oct 20, 2020
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