(HealthDay)—Melanomas diagnosed through routine skin checks are associated with significantly lower all-cause mortality, but not with lower melanoma-specific mortality after adjustment for prognostic factors, according ...
Nov 03, 2021
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A potentially game-changing trial involving University of Liverpool researchers has shown how an immunotherapy drug can prolong the life of patients with an aggressive form of eye cancer.
Nov 03, 2021
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New research shows that testosterone promotes melanoma proliferation by activating a newly recognized nonclassical testosterone receptor in melanoma cells called ZIP9 (encoded by the SLC39A9 gene), a zinc transporter that ...
Oct 27, 2021
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(HealthDay)—A direct-to-consumer machine learning model for detecting skin cancers may not adequately recognize rare, but aggressive, skin cancers, according to a study presented at the annual meeting of the European Academy ...
Oct 14, 2021
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Immunotherapy, which harnesses the power of the body's immune system to fight disease, is gaining huge traction in treating cancer. Chief among cancer immunotherapies is a treatment known as CAR-T, or chimeric antigen receptor ...
Oct 04, 2021
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Recent advances in immunotherapy have allowed doctors at the University of Colorado Cancer Center to more effectively treat melanomas that spread to other parts of the body. Immunotherapy drugs such as checkpoint inhibitors, ...
Sep 23, 2021
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The first randomised phase III clinical trial in stage II melanoma has shown a 35% reduction in the risk of recurrence with adjuvant pembrolizumab compared with placebo. The late breaking results of the KEYNOTE-716 trial are presented ...
Sep 20, 2021
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An immunotherapy called pembrolizumab reduced cancer recurrence after surgery in patients with stage IIb and IIc melanoma, according to the results of an international, randomized phase III clinical trial led by UPMC Hillman ...
Sep 20, 2021
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Hokkaido University scientists and colleagues in Japan have found a way that could help some patients overcome resistance to an immunotherapy treatment for cancer. The approach, proven in mice experiments, was reported in ...
Sep 17, 2021
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In the progressing field of immunotherapy, surprisingly little is known about immunity to metastatic tumors in locations such as lymph nodes, a frequent place where cancers first spread. Not only do lymph nodes act as a gateway ...
Sep 14, 2021
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Melanoma (pronounced /ˌmɛləˈnoʊmə/ ( listen)) is a malignant tumor of melanocytes which are found predominantly in skin but also in the bowel and the eye (see uveal melanoma). It is one of the less common types of skin cancer but causes the majority of skin cancer related deaths. Malignant melanoma is a serious type of skin cancer. It is due to uncontrolled growth of pigment cells, called melanocytes. Despite many years of intensive laboratory and clinical research, the sole effective cure is surgical resection of the primary tumor before it achieves a Breslow thickness greater than 1 mm.
Around 160,000 new cases of melanoma are diagnosed nationally each year, and it is more frequent in males and Caucasians. It is more common in Caucasian populations living in sunny climates than in other groups. According to a WHO report about 48,000 melanoma related deaths occur worldwide per year.
Malignant melanoma accounts for 75 percent of all deaths associated with skin cancer.
The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy.
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