Oncology & Cancer

Study reveals source of DNA mutations in melanoma

The mutations that give rise to melanoma result from a chemical conversion in DNA fueled by sunlight—not just a DNA copying error as previously believed, reports a study by Van Andel Institute scientists published today ...

Oncology & Cancer

Antibiotics may help to treat melanoma

Some antibiotics appear to be effective against a form of skin cancer known as melanoma. Researchers at KU Leuven, Belgium, examined the effect of these antibiotics on patient-derived tumors in mice. Their findings were published ...

Oncology & Cancer

Melanoma of the eye: Preclinical tests show path toward treatment

Uveal melanoma, or UM, is a rare and deadly cancer of the eye, and the mortality rate has remained unimproved for 40 years. Half of the melanomas spread to other organs of the body, causing death in less than a year, so new ...

Oncology & Cancer

A new approach to metastatic melanoma discovered

Combining chemotherapy and BRAF oncogene inhibitors is an effective strategy for fighting metastatic melanoma, the leading cause of death from skin cancer in the world. This has been demonstrated in a study by researchers ...

Diseases, Conditions, Syndromes

Q and A: Bleeding moles and skin checks

DEAR MAYO CLINIC: I have a significant number of moles. While most do not bother me, I have at least one that bleeds from time to time. Should I see my doctor for a mole that bleeds?

Oncology & Cancer

Melanoma registry results shine light on rare pediatric cancer

Pediatric melanoma is a rare disease with only around 400 cases diagnosed in the United States every year. To better understand this disease and how best to treat it, St. Jude Children's Research Hospital scientists created ...

Oncology & Cancer

Physical activity does not increase the risk of melanoma

It is safe to be physically active outdoors without having to worry about the risk of melanoma, as long as you follow the sun safety advice, say the researchers behind a large Norwegian study.

Oncology & Cancer

Cell-based immunotherapy shows promise against melanoma

An immunotherapy based on supercharging the immune system's natural killer cells has been effective in treating patients with recurrent leukemia and other difficult to treat blood cancers. Now, researchers at Washington University ...

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Melanoma

Melanoma (pronounced /ˌmɛləˈnoʊmə/ ( listen)) is a malignant tumor of melanocytes which are found predominantly in skin but also in the bowel and the eye (see uveal melanoma). It is one of the less common types of skin cancer but causes the majority of skin cancer related deaths. Malignant melanoma is a serious type of skin cancer. It is due to uncontrolled growth of pigment cells, called melanocytes. Despite many years of intensive laboratory and clinical research, the sole effective cure is surgical resection of the primary tumor before it achieves a Breslow thickness greater than 1 mm.

Around 160,000 new cases of melanoma are diagnosed nationally each year, and it is more frequent in males and Caucasians. It is more common in Caucasian populations living in sunny climates than in other groups. According to a WHO report about 48,000 melanoma related deaths occur worldwide per year.

Malignant melanoma accounts for 75 percent of all deaths associated with skin cancer.

The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy.

This text uses material from Wikipedia, licensed under CC BY-SA