Oncology & Cancer

Research explores how melanoma grows and spreads

The first step in treating cancer is understanding how it starts, grows and spreads throughout the body. A relatively new cancer research approach is the study of metabolites, the products of different steps in cancer cell ...

Oncology & Cancer

Ultraviolet radiation causes rare type of eye cancer

Ultraviolet radiation can cause a rare type of eye cancer, conjunctival melanoma, according to research funded by Cancer Research UK and others and published in Nature Communications today.

Oncology & Cancer

An epidemic of overdiagnosis: Melanoma diagnoses skyrocket

In a Sounding Board article published in The New England Journal of Medicine, H. Gilbert Welch MD, MPH, Senior Investigator, Center for Surgery and Public Health, Brigham and Women's Hospital and colleagues present evidence ...

Oncology & Cancer

Immune checkpoint inhibitor therapy tied to cardiac event risk

(HealthDay)—Immune checkpoint inhibitor (ICI) treatment is associated with increased cardiac events among patients with lung cancer and malignant melanoma, according to a study published online Dec. 9 in the European Heart ...

Oncology & Cancer

Researchers identify promising drug combination for melanoma

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) have identified a potential drug combination to treat uveal melanoma, a type of eye cancer. Lead author Amanda Truong, trainee in the McMahon ...

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Melanoma

Melanoma (pronounced /ˌmɛləˈnoʊmə/ ( listen)) is a malignant tumor of melanocytes which are found predominantly in skin but also in the bowel and the eye (see uveal melanoma). It is one of the less common types of skin cancer but causes the majority of skin cancer related deaths. Malignant melanoma is a serious type of skin cancer. It is due to uncontrolled growth of pigment cells, called melanocytes. Despite many years of intensive laboratory and clinical research, the sole effective cure is surgical resection of the primary tumor before it achieves a Breslow thickness greater than 1 mm.

Around 160,000 new cases of melanoma are diagnosed nationally each year, and it is more frequent in males and Caucasians. It is more common in Caucasian populations living in sunny climates than in other groups. According to a WHO report about 48,000 melanoma related deaths occur worldwide per year.

Malignant melanoma accounts for 75 percent of all deaths associated with skin cancer.

The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy.

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