Parkinson's disease, a neurodegenerative disorder that affects more than 6 million people worldwide, is caused by the buildup of alpha-synuclein proteins in the brain. The biological function of alpha-synuclein is still not ...
Jul 3, 2019
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The amyloid precursor protein has always been vilified as a major cause of Alzheimer's disease. One of its fragments, the amyloid-beta peptide, can break off and accumulate in the brain, giving rise to the puffy white globs ...
Jun 14, 2019
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The ability to hear depends on proteins to reach the outer membrane of sensory cells in the inner ear. But in certain types of hereditary hearing loss, mutations in the protein prevent it from reaching these membranes. Using ...
Jun 11, 2019
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Cells missing a certain protein on their surface can't move normally, UConn researchers report in Science Signaling. The research could give insight into how cells move and repair wounds in normal tissue, as well as how cancer ...
May 3, 2019
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Influenza is ubiquitous. Every fall, we line up to get our flu shots with the hope that we will be protected from the virus that infects 10 to 20 percent of people worldwide each year. But some years, the vaccine is less ...
Apr 23, 2019
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An approved drug normally used to treat fungal infections could also do the job of a protein channel that is missing in the lungs of people with cystic fibrosis, operating as a prosthesis on the molecular scale, says new ...
Mar 13, 2019
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The release of neurotransmitters and hormones in the body is tightly controlled by complex protein machinery embedded in cell membranes.
Mar 8, 2019
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The aggregation of alpha-synuclein proteins in Parkinson's disease and tau proteins in Alzheimer's disease is intimately linked to the progression of these neurodegenerative diseases. These aggregates propagate from one neuronal ...
Mar 8, 2019
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New research on how cancer mutations influence a certain type of receptor on the cell membrane opens the way for the development of tailored drugs for certain cancers, such as rectal cancer and lung cancer. This, according ...
Feb 11, 2019
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A molecular pathway that's frequently mutated in many different forms of cancer becomes active when cells push parts of their membranes outward into bulging protrusions, Johns Hopkins researchers report in a new study. The ...
Dec 11, 2018
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