The rod-like spike proteins on the surface of SARS CoV-2 are the tip of the spear of the COVID-19 pandemic. The spikes bind to human cells via the ACE2 receptor and then dramatically change shape, jack-knifing to fuse the ...
Jul 21, 2020
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Sufferers of Parkinson's disease have clumps of α-synuclein (alpha-synuclein), sometimes known as the "Parkinson's protein," found in the brain. These destroy cell membranes, eventually resulting in cell death. Now, a method ...
Jul 2, 2020
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The brains of people suffering from Alzheimer's disease (AD) are slowly and inescapably being depleted of neurons, which leads to the characteristic loss of memory and cognitive function associated with this condition. However, ...
Jun 29, 2020
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A protein shredder that occurs in cell membranes of brain cells apparently also indirectly regulates the fat metabolism. This is shown by a recent study by the University of Bonn. The shredder, known as gamma-secretase, is ...
May 8, 2020
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A new study reveals the mechanism that helps pancreatic cancer cells avoid starvation within dense tumors by hijacking a process that pulls nutrients in from their surroundings.
Dec 11, 2019
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Cystic fibrosis is caused by an inherited mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Due to this mutation, the CFTR protein doesn't embed in cell membranes to form a channel for chlorine ...
Dec 10, 2019
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Glutamate receptors in the brain called AMPARs are critical for synaptic plasticity, learning and memory. Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, ...
Dec 9, 2019
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Together with colleagues from Shanghai, Brussels, Canada and the USA, researchers from the University of Bonn have uncovered the binding mechanism of an important pain receptor. The results facilitate the development of new ...
Nov 27, 2019
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It is generally known that viruses, with their cell-invading capabilities, can be responsible for a number of different cancers. What is less broadly discussed are the cancer-causing capabilities of bacteria, or the processes ...
Nov 18, 2019
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Parkinson's disease, a neurodegenerative disorder that affects more than 6 million people worldwide, is caused by the buildup of alpha-synuclein proteins in the brain. The biological function of alpha-synuclein is still not ...
Jul 3, 2019
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