PIK3CA is a gene that makes an enzyme called PI3K, which is involved in many important cell functions. When PIK3CA mutates, however, it can make the PI3K enzyme become overactive and cause cancer cells to grow.
Jul 8, 2022
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University of Alberta scientists have identified a receptor in cells that could be key to preventing permanent hearing loss in childhood cancer survivors who are being treated with the drug cisplatin. The researchers believe ...
May 14, 2021
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SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells. Professor Johanna Ivaska's research group at Turku Bioscience observed that SORLA functionally contributes ...
Jan 29, 2021
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Permanent hearing loss triggered by a common chemotherapy drug in half of children being treated for cancer may occur through a well-studied immune receptor, according to University of Alberta research.
Aug 17, 2020
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Despite many developments in the diagnosis and treatment of gastric cancer, it continues to be an important public health problem. Therefore, besides classical methods, new biomolecules are needed to facilitate the prediction ...
Jul 13, 2020
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Spending a lot more time in your house doesn't have to make you any less curious about the world around you. Just look inside your kitchen cupboards and there's a wealth of chemistry just bursting to get out. Here are some ...
Apr 2, 2020
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New research on how cancer mutations influence a certain type of receptor on the cell membrane opens the way for the development of tailored drugs for certain cancers, such as rectal cancer and lung cancer. This, according ...
Feb 11, 2019
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In just a few years, CAR T-cell and other adoptive T-cell therapies have emerged as among the most promising forms of cancer immunotherapy. But even as these agents prove themselves against several forms of leukemia and lymphoma—and, ...
Oct 30, 2018
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A team of Massachusetts General Hospital (MGH) Cancer Center researchers has determined one way that mutations in a gene involved in a rare, hereditary cancer syndrome lead to out-of-control cellular proliferation. In their ...
Aug 28, 2018
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In contrast to most antidepressant medications, which can take several weeks to reduce depressive symptoms, ketamine—a commonly used veterinary anesthetic—can lift a person out of a deep depression within minutes of its ...
Jun 21, 2018
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