Neuroscience

New tool for watching and controlling neural activity

A new molecular probe from Stanford University could help reveal how our brains think and remember. This tool, called Fast Light and Calcium-Regulated Expression or FLiCRE (pronounced "flicker"), can be sent inside any cell ...

Diseases, Conditions, Syndromes

A sulfur molecule to block the coronavirus

The cell membrane is impermeable to viruses—to get inside and infect a cell, they use a range of strategies to exploit the cellular and biochemical properties of the membranes. The thiol-mediated uptake of organic molecules ...

Medical research

Chronic inflammation causes a reduction in NAD+

NAD+ (nicotinamide adenine dinucleotide), a key metabolite central to an efficient and healthy metabolism, declines with age. This previously unexplained phenomena is associated with numerous age-related diseases and has ...

Medical research

An unconventional ion channel

Scientists at Ludwig-Maximilians-Universitaet (LMU) in Munich have identified the first mechanosensitive ion channel to be found in an intracellular vesicle system. It responds to concentration changes within the vesicle, ...

Immunology

Researchers uncover new mechanism of immune-cell activation

When antibody-producing immune cells encounter infectious pathogens for the first time, they engage a signal cascade to generate a massive activation signal within seconds. The mechanisms underlying this acute initial activation ...

Medical research

Cholesterol's effects on cellular membranes

For more than a decade, scientists have accepted that cholesterol—a key component of cell membranes—did not uniformly affect membranes of different types. But a new study led by Assistant Professor Rana Ashkar of the ...

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