Mice with a strong tendency to obesity already exhibit epigenetic changes at six weeks of age, inducing the liver to amplify its production of the enzyme DPP4 and release it into the circulation. Over the long term, this ...
Jan 10, 2017
0
0
The tuberculosis vaccine is well known to help protect against other infectious diseases, as well as cancer, but the exact mechanisms have not been clear. A study published December 6 in Cell Reports now shows that the broad-spectrum ...
Dec 6, 2016
0
161
Individuals with Li-Fraumeni syndrome are at an increased risk for a number of cancers, including breast and bone cancer. Li-Fraumeni syndrome is an inherited cancer disorder caused by mutations in the tumor suppressing protein ...
Nov 21, 2016
0
30
About one third of cancer patients die because of cachexia - an involuntary weight loss, characterized primarily by muscle wasting and metabolic changes, which cannot be addressed or treated solely with increased food intake. ...
Nov 4, 2016
0
0
Obesity is a well-known risk factor for osteoarthritis, but its effects on cartilage repair are unknown. In a recent study in a mouse model of cartilage repair, a high-fat diet and increased body weight did not negatively ...
Jul 19, 2016
0
0
Scientists of the German Center for Diabetes Research (DZD), led by the German Institute of Human Nutrition (DIfE), have demonstrated that the epigenetic modification of the Igfbp2 gene observed in young mice precedes fatty ...
May 24, 2016
0
6
The fates of immune cells can be decided at the initial division of a cell. Researchers at St. Jude Children's Research Hospital have discovered that the production of daughter cells with different roles in the immune system ...
Apr 11, 2016
0
143
Australian researchers have found biochemical changes occurring in the blood, in the rare inherited form of Alzheimer's disease. Changes in these fat-like substances, may suggest a method to diagnose all forms of Alzheimer's ...
Feb 9, 2016
0
14
As the study shows, a high-fat diet during pregnancy and lactation leads to epigenetic changes in the offspring. These changes affect metabolic pathways regulated by the gut hormone GIP, whereby the adult offspring are more ...
Feb 1, 2016
0
1
Roughly twenty years before the first symptoms of Alzheimer's disease appear, inflammatory changes in the brain can be seen, according to a new study from Karolinska Institutet published in the medical scientific journal ...
Jan 27, 2016
1
175
