Arthritis & Rheumatism

High-fat diet improves cartilage repair in mice

Obesity is a well-known risk factor for osteoarthritis, but its effects on cartilage repair are unknown. In a recent study in a mouse model of cartilage repair, a high-fat diet and increased body weight did not negatively ...

Alzheimer's disease & dementia

Evidence of a lipid link in the inherited form of Alzheimer's disease

Australian researchers have found biochemical changes occurring in the blood, in the rare inherited form of Alzheimer's disease. Changes in these fat-like substances, may suggest a method to diagnose all forms of Alzheimer's ...

Diabetes

When food alters gene function

As the study shows, a high-fat diet during pregnancy and lactation leads to epigenetic changes in the offspring. These changes affect metabolic pathways regulated by the gut hormone GIP, whereby the adult offspring are more ...

Alzheimer's disease & dementia

Inflammatory changes in the brain twenty years before Alzheimer onset

Roughly twenty years before the first symptoms of Alzheimer's disease appear, inflammatory changes in the brain can be seen, according to a new study from Karolinska Institutet published in the medical scientific journal ...

Medical research

What metabolism could reveal about aging and mortality

Why some people live much longer than others is an enduring mystery. Now, based on a study of a worm, scientists are getting one step closer to understanding longevity. They report in ACS' Journal of Proteome Research that ...

Cardiology

Do hearts fail because they're hooked on blood sugar?

Could your heart get hooked on blood sugar? Researchers at the University of Virginia School of Medicine think so, and they will determine if blocking that addiction could prevent enlargement of the heart that can lead to ...

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