Genetics

Genetic variation determines response to anti-diabetic drug

In the first study of its kind, Penn researchers have shown how an anti-diabetic drug can have variable effects depending on small natural differences in DNA sequence between individuals. Mitchell Lazar, MD, PhD, Raymond ...

Diabetes

Diabetes drugs affect hearts of men, women differently

(Medical Xpress)—Widely used treatments for type 2 diabetes have different effects on the hearts of men and women, even as the drugs control blood sugar equally well in both sexes, according to researchers at Washington ...

Diseases, Conditions, Syndromes

Sex differences in kidney gene expression

Male and female rats show different patterns of kidney gene expression throughout their lives, a study in the open access journal Biology of Sex Differences reveals. The finding could help explain some of the gender differences ...

Medical research

Do men's and women's hearts burn fuel differently?

Researchers at the University of Illinois at Chicago College of Medicine will study gender differences in how the heart uses and stores fat—its main energy source—and how changes in fat metabolism play a role in heart ...

Oncology & Cancer

Scientists find potential loophole in pancreatic cancer defenses

Dana-Farber Cancer Institute scientists and colleagues have discovered that pancreatic cancer cells' growth and spread are fueled by an unusual metabolic pathway that someday might be blocked with targeted drugs to control ...

Health

Perception and preference may have genetic link to obesity

About five years ago, animal studies first revealed the presence of entirely novel types of oral fat sensors or receptors on the tongue. Prior to this time, it was believed that fats were perceived only by flavor and texture ...

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