Yale scientists have identified a way to "supercharge" tumor-attacking T cells, a finding that may not only improve the effectiveness of a promising type of cell-based cancer immunotherapy but also expand the number of cancers ...
Mar 10, 2022
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466
Researchers have identified a metabolic enzyme and pathway in some triple-negative breast cancer (TNBC) patients, which they hope could serve as a biomarker to select patients to receive targeted therapy.
Nov 16, 2021
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55
Glioblastoma is the most lethal and malignant adult brain cancer that may arise from neuroglial stem or progenitor cells. Certain gene mutations or those with a known history of other cancers and radiation therapy may predispose ...
Sep 15, 2021
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62
The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This was discovered by scientists at the German Cancer Research Center (DKFZ) and the Berlin Institute ...
Aug 20, 2020
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82
Using human lung cancer cells, UT Southwestern researchers have uncovered how cells in general modulate their energy consumption based on their surroundings and, furthermore, how cancer cells override those cues to maximize ...
Feb 24, 2020
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136
A popular cancer drug is associated with significant weight gain and increased systolic blood pressure, researchers from the Icahn School of Medicine at Mount Sinai report in a study published in Scientific Reports in November.
Nov 12, 2019
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31
Blocking the action of an enzyme involved in protein digestion may improve metabolic health, according to a new study published ahead of print in the American Journal of Physiology—Gastrointestinal and Liver Physiology. ...
May 8, 2019
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A systematic examination of the tumor and the tissue surrounding it—particularly normal cells in that tissue, called fibroblasts—has revealed a new treatment target that could potentially prevent the rapid dissemination ...
May 1, 2019
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210
Columbia University scientists, in collaboration with researchers from Nimbus Therapeutics, have demystified a metabolic enzyme that could be the next major molecular target in cancer treatment.
Apr 3, 2019
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34
Scientists have discovered a novel molecular pathway for an enzyme inhibitor in humans that plays a direct role in the development of high cholesterol and nonalcoholic fatty liver disease, which they then were able to reverse ...
Mar 25, 2019
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