Cancerous tumors must be fed. Their unregulated growth requires a steady stream of blood flow and nutrients. Thus, one way that researchers have tried to wipe out cancer is to target cells undergoing the metabolic shifts ...
Jul 6, 2016
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Around-the-clock rhythms guide nearly all physiological processes in animals and plants. Each cell in the body contains special proteins that act on one another in interlocking feedback loops to generate near-24 hour oscillations ...
Jun 4, 2015
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New research has found that a variant of a drug used to treat pulmonary arterial hypertension prompts weight loss in obese mice. Among mice fed a high-fat diet, those who did not get the medication became obese while medicated ...
May 28, 2015
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New research demonstrates that obesity does not always go hand in hand with metabolic changes in the body that can lead to diabetes, heart disease and stroke.
Jan 2, 2015
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An Indiana University study has found that three easy—one could even say slow—5-minute walks can reverse harm caused to leg arteries during three hours of prolonged sitting.
Sep 8, 2014
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Much of the liver's metabolic function is governed by circadian rhythms – our own body clock – and UC Irvine researchers have now found two independent mechanisms by which this occurs.
Jul 31, 2014
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In the most comprehensive exploration of the association between genetic variation and human metabolism, researchers have provided unprecedented insights into how genetic variants influence complex disease and drug response ...
May 11, 2014
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When the tiny roundworm C. elegans reaches middle age—at about 2 weeks old—it can't quite move like it did in the bloom of youth. But rather than imposing an exercise regimen to rebuild the worm's body-wall muscles, researchers ...
Sep 3, 2013
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A team led by researchers at the National Institutes of Health has overcome a major biological hurdle in an effort to find improved treatments for patients with a rare disease called methylmalonic acidemia (MMA). Using genetically ...
Jul 29, 2013
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Research from three Yale laboratories—in the fields of immunobiology, chemistry, and cardiology—could lead to new drugs to reduce complications during cardiac surgery or heart attacks. If they pan out in human trials, ...
Jul 24, 2013
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